articleNeuroImageOct 22, 2014HYBRID OA

Accelerated Microstructure Imaging via Convex Optimization (AMICO) from diffusion MRI data

École Polytechnique Fédérale de Lausanne · University of Lausanne · +6 more institutions

PubMed
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Abstract

Microstructure imaging from diffusion magnetic resonance (MR) data represents an invaluable tool to study non-invasively the morphology of tissues and to provide a biological insight into their microstructural organization. In recent years, a variety of biophysical models have been proposed to associate particular patterns observed in the measured signal with specific microstructural properties of the neuronal tissue, such as axon diameter and fiber density. Despite very appealing results showing that the estimated microstructure indices agree very well with histological examinations, existing techniques require computationally very expensive non-linear procedures to fit the models to the data which, in…

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