reviewChemical Society ReviewsJan 1, 2013Closed access

C–N bond forming cross-coupling reactions: an overview

Indo Soviet Friendship College of Pharmacy · KU Leuven

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Abstract

Nitrogen containing compounds are of great importance because of their interesting and diverse biological activities. The construction of the C-N bond is of significant importance as it opens avenues for the introduction of nitrogen in organic molecules. Despite significant advancements in this field, the construction of the C-N bond is still a major challenge for organic chemists, due to the involvement of harsh reaction conditions or the use of expensive catalysts in many cases. Thus, it is a challenge to develop alternative, milder and cheaper methodologies for the construction of C-N bonds. Herein, we have selected some prime literature reports that may serve this purpose.

Citation impact

998
total citations
FWCI
26.94
Percentile
100%
References
53
Citations per year

Authors

2

Topics & keywords

Keywords
  • Bond
  • Biochemical engineering
  • Nanotechnology
  • Chemistry
  • Coupling reaction
  • Organic molecules
  • Combinatorial chemistry
  • Catalysis
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