Lipid-Based Nanoparticles as Pharmaceutical Drug Carriers: From Concepts to Clinic
National Institutes of Health · Center for Cancer Research · +5 more institutions
Abstract
In recent years, various nanotechnology platforms in the area of medical biology, including both diagnostics and therapy, have gained remarkable attention. Moreover, research and development of engineered multifunctional nanoparticles as pharmaceutical drug carriers have spurred exponential growth in applications to medicine in the last decade. Design principles of these nanoparticles, including nanoemulsions, dendrimers, nano-gold, liposomes, drug-carrier conjugates, antibody-drug complexes, and magnetic nanoparticles, are primarily based on unique assemblies of synthetic, natural, or biological components, including but not limited to synthetic polymers, metal ions, oils, and lipids as their building blocks.…
Citation impact
- FWCI
- 9.03
- Percentile
- 100%
- References
- 255
Authors
7- APAnu PuriCorresponding
National Institutes of Health, Center for Cancer Research, Frederick National Laboratory for Cancer Research, National Cancer Institute
- KHKristin H. Loomis
Emory University, Georgia Institute of Technology
- BSBrandon Smith
Frederick National Laboratory for Cancer Research, National Cancer Institute, Center for Cancer Research, National Institutes of Health
- JHJae Ho Lee
Frederick National Laboratory for Cancer Research, National Institutes of Health, Center for Cancer Research, National Cancer Institute
- AYAmichai Yavlovich
National Cancer Institute, National Institutes of Health, Center for Cancer Research, Frederick National Laboratory for Cancer Research
Topics & keywords
- Nanotechnology
- Drug delivery
- Nanoparticle
- Liposome
- Solid lipid nanoparticle
- Drug carrier
- Drug
- Targeted drug delivery