Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
Cornell University · Memorial Sloan Kettering Cancer Center · +8 more institutions
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Abstract
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2,727
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26Topics & keywords
Topics
Keywords
- IDH2
- Phenotype
- IDH1
- Haematopoiesis
- Biology
- Function (biology)
- Cancer research
- DNA methylation
UN Sustainable Development Goals
- Good health and well-being
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