reviewHepatologyNov 26, 2011BRONZE OA

The global burden of hepatitis E virus genotypes 1 and 2 in 2005

DBDavid B. ReinGAGretchen A StevensJTJordan TheakerJSJohn S. WittenbornSWSteven Wiersma

Norwich University · University of Chicago · +4 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

UNLABELLED: We estimated the global burden of hepatitis E virus (HEV) genotypes 1 and 2 in 2005. HEV is an emergent waterborne infection that causes source-originated epidemics of acute disease with a case fatality rate thought to vary by age and pregnancy status. To create our estimates, we modeled the annual disease burden of HEV genotypes 1 and 2 for 9 of 21 regions defined for the Global Burden of Diseases, Injuries, and Risk Factors Study (the GBD 2010 Study), which represent 71% of the world's population. We estimated the seroprevalence of anti-HEV antibody and annual incidence of infection for each region using data from 37 published national studies and the DISMOD 3, a generic disease model designed…

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Authors

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Topics & keywords

Topics
Keywords
  • Virology
  • Genotype
  • Medicine
  • Hepatitis a virus
  • Virus
  • Biology
  • Genetics
  • Gene
UN Sustainable Development Goals
  • Good health and well-being
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