Prospective Study of Obstructive Sleep Apnea and Incident Coronary Heart Disease and Heart Failure
Boston University · Harvard University · +8 more institutions
Abstract
BACKGROUND: Clinic-based observational studies in men have reported that obstructive sleep apnea is associated with an increased incidence of coronary heart disease. The objective of this study was to assess the relation of obstructive sleep apnea to incident coronary heart disease and heart failure in a general community sample of adult men and women. METHODS AND RESULTS: A total of 1927 men and 2495 women > or =40 years of age and free of coronary heart disease and heart failure at the time of baseline polysomnography were followed up for a median of 8.7 years in this prospective longitudinal epidemiological study. After adjustment for multiple risk factors, obstructive sleep apnea was a significant…
Citation impact
- FWCI
- 43.71
- Percentile
- 100%
- References
- 51
Authors
11- DJDaniel J. GottliebCorresponding
Boston University, Harvard University, University of Arizona, Johns Hopkins University, University of Pittsburgh, Georgetown University, VA Boston Healthcare System, Leading Age, Case Western Reserve University, University of California, Davis
- GYGayane Yenokyan
Boston University, Harvard University, University of Arizona, Johns Hopkins University, University of Pittsburgh, Georgetown University, VA Boston Healthcare System, Leading Age, Case Western Reserve University, University of California, Davis
- ABAnne B. Newman
Boston University, Harvard University, University of Arizona, Johns Hopkins University, University of Pittsburgh, Georgetown University, VA Boston Healthcare System, Leading Age, Case Western Reserve University, University of California, Davis
- GOGeorge O'connor
Boston University, Harvard University, University of Arizona, Johns Hopkins University, University of Pittsburgh, Georgetown University, VA Boston Healthcare System, Leading Age, Case Western Reserve University, University of California, Davis
- NMNaresh M. Punjabi
Boston University, Harvard University, University of Arizona, Johns Hopkins University, University of Pittsburgh, Georgetown University, VA Boston Healthcare System, Leading Age, Case Western Reserve University, University of California, Davis
Topics & keywords
- Medicine
- Obstructive sleep apnea
- Hazard ratio
- Heart failure
- Myocardial infarction
- Cardiology
- Internal medicine
- Polysomnography
- Good health and well-being