articleNatureNov 22, 2009GREEN OA

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

LDLenny DangDWDavid W. WhiteSGStefan GrößBDBryson D. BennettMBMark Bittinger

Agios Pharmaceuticals (United States) · Princeton University · +5 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

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Citation impact

4,113
total citations
FWCI
65.45
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100%
References
27
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Authors

20

Topics & keywords

Topics
Keywords
  • Isocitrate dehydrogenase
  • IDH1
  • Oxidative decarboxylation
  • Enzyme
  • Mutation
  • Biochemistry
  • Biology
  • Cancer research
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