GalaxyWEB server for protein structure prediction and refinement
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Abstract
Three-dimensional protein structures provide invaluable information for understanding and regulating biological functions of proteins. The GalaxyWEB server predicts protein structure from sequence by template-based modeling and refines loop or terminus regions by ab initio modeling. This web server is based on the method tested in CASP9 (9th Critical Assessment of techniques for protein Structure Prediction) as 'Seok-server', which was assessed to be among top performing template-based modeling servers. The method generates reliable core structures from multiple templates and re-builds unreliable loops or termini by using an optimization-based refinement method. In addition to structure prediction, a user can…
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4Topics & keywords
Topics
Keywords
- Web server
- Server
- Template
- Biology
- Computer science
- Protein structure prediction
- Computational biology
- Protein structure
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