reviewInternational Journal of Molecular SciencesJan 14, 2013GOLD OA

Biopolymer-Based Nanoparticles for Drug/Gene Delivery and Tissue Engineering

RIKEN Center for Sustainable Resource Science

PubMed
Indexed incrossrefdoajpubmed

Abstract

There has been a great interest in application of nanoparticles as biomaterials for delivery of therapeutic molecules such as drugs and genes, and for tissue engineering. In particular, biopolymers are suitable materials as nanoparticles for clinical application due to their versatile traits, including biocompatibility, biodegradability and low immunogenicity. Biopolymers are polymers that are produced from living organisms, which are classified in three groups: polysaccharides, proteins and nucleic acids. It is important to control particle size, charge, morphology of surface and release rate of loaded molecules to use biopolymer-based nanoparticles as drug/gene delivery carriers. To obtain a nano-carrier for…

Citation impact

656
total citations
FWCI
22.53
Percentile
100%
References
186
Citations per year

Authors

2

Topics & keywords

Keywords
  • Biopolymer
  • Biocompatibility
  • Drug delivery
  • Gelatin
  • Gene delivery
  • Nanoparticle
  • Tissue engineering
  • Nanotechnology
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