Statin Therapy Accelerates Reendothelialization
St. Elizabeth's Medical Center
Indexed incrossrefpubmed
Abstract
BACKGROUND: Primary and secondary prevention trials suggest that statins possess favorable effects independent of cholesterol reduction. We investigated whether statin therapy may also accelerate reendothelialization after carotid balloon injury. METHODS AND RESULTS: Simvastatin treatment in 34 male Sprague-Dawley rats accelerated reendothelialization of the balloon-injured arterial segments (reendothelialized area at 2 weeks, 12.3+/-1.8 versus 5.4+/-1.1 mm2, P
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914
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Authors
10Topics & keywords
Topics
Keywords
- Medicine
- Simvastatin
- Progenitor cell
- Bone marrow
- Statin
- Transplantation
- Artery
- Immunohistochemistry
UN Sustainable Development Goals
- Good health and well-being
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