Diurnal Variation of Choroidal Thickness in Normal, Healthy Subjects Measured by Spectral Domain Optical Coherence Tomography
Singapore National Eye Center · Tan Tock Seng Hospital · +3 more institutions
Abstract
A prospective study was conducted on 12 healthy volunteers who each underwent sequential ocular imaging on two separate days at five fixed, 2-hour time intervals. Spectral domain optical coherence tomography (OCT) with enhanced depth imaging and image tracking was performed using a standardized protocol. Choroidal and retinal thicknesses were independently assessed by two masked graders. CT diurnal variation was assessed using repeated-measures ANOVA.
A significant diurnal variation in CT was observed, with mean maximum CT of 372.2 μm, minimum of 340.6 μm (P
Citation impact
- FWCI
- 36.59
- Percentile
- 100%
- References
- 44
Authors
4- CSColin S. TanCorresponding
Singapore National Eye Center, Tan Tock Seng Hospital, Doheny Eye Institute, Singapore Eye Research Institute
- YOYanling Ouyang
University of Southern California, Doheny Eye Institute
- HRHumberto Ruiz
University of Southern California, Doheny Eye Institute
- SRSriniVas R. Sadda
University of Southern California, Doheny Eye Institute
Topics & keywords
- Diurnal temperature variation
- Optical coherence tomography
- Morning
- Reproducibility
- Ophthalmology
- Medicine
- Coefficient of variation
- Retinal