Adverse Drug Reactions in Hospital In-Patients: A Prospective Analysis of 3695 Patient-Episodes
Royal Liverpool and Broadgreen University Hospital NHS Trust · Liverpool John Moores University · +2 more institutions
Abstract
Adverse drug reactions (ADRs) are a major cause of hospital admissions, but recent data on the incidence and clinical characteristics of ADRs which occur following hospital admission, are lacking. Patients admitted to twelve wards over a six-month period in 2005 were assessed for ADRs throughout their admission. Suspected ADRs were recorded and analysed for causality, severity and avoidability and whether they increased the length of stay. Multivariable analysis was undertaken to identify the risk factors for ADRs. The 5% significance level was used when assessing factors for inclusion in multivariable models. Out of the 3695 patient episodes assessed for ADRs, 545 (14.7%, 95% CI 13.6-15.9%) experienced one or…
Citation impact
- FWCI
- 17.29
- Percentile
- 100%
- References
- 59
Authors
6- EDEmma Davies
Royal Liverpool and Broadgreen University Hospital NHS Trust, Liverpool John Moores University
- CFChristopher F. Green
Countess of Chester Hospital NHS Foundation Trust
- STStephen Taylor
University of Liverpool
- PWPaula Williamson
University of Liverpool
- DRDavid R. Mottram
Liverpool John Moores University
Topics & keywords
- Medicine
- Drug reaction
- Incidence (geometry)
- Pediatrics
- Pharmacoepidemiology
- Emergency medicine
- Hazard ratio
- Internal medicine
- Good health and well-being