Prevalence of Neuropsychiatric Symptoms in Dementia and Mild Cognitive Impairment
Johns Hopkins University · University of Pittsburgh · +6 more institutions
Abstract
To estimate the prevalence of neuropsychiatric symptoms in dementia and MCI in a population-based study.
Cross-sectional study derived from the Cardiovascular Health Study, a longitudinal cohort study. SETTING AND PARTICIPANTS: A total of 3608 participants were cognitively evaluated using data collected longitudinally over 10 years and additional data collected in 1999-2000 in 4 US counties. Dementia and MCI were classified using clinical criteria and adjudicated by committee review by expert neurologists and psychiatrists. A total of 824 individuals completed the Neuropsychiatric Inventory (NPI); 362 were classified as having dementia, 320 as having MCI; and 142 did not meet criteria for MCI or dementia. MAIN OUTCOME MEASURE: Prevalence of neuropsychiatric symptoms, based on ratings on the NPI in the previous month and from the onset of cognitive symptoms.
Citation impact
- FWCI
- 21.38
- Percentile
- 100%
- References
- 59
Authors
6- CGConstantine G. LyketsosCorresponding
Johns Hopkins University
- OLOscar L. López
Johns Hopkins University
- BNBeverly N. Jones
University of Pittsburgh
- ALAnnette L. Fitzpatrick
Wake Forest University
- JCJohn C.S. Breitner
Johns Hopkins University, University of Pittsburgh, VA Puget Sound Health Care System, Geriatric Research Education and Clinical Center, University of Washington, Wake Forest University, Forsyth County Schools, Johns Hopkins Hospital
Topics & keywords
- Apathy
- Dementia
- Medicine
- Irritability
- Depression (economics)
- Psychiatry
- Cohort
- Population
- Good health and well-being