One-Pot Synthesis of Protein-Embedded Metal–Organic Frameworks with Enhanced Biological Activities
Tsinghua University · Stanford University
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Abstract
Protein molecules were directly embedded in metal-organic frameworks (MOFs) by a coprecipitation method. The protein molecules majorly embedded on the surface region of MOFs display high biological activities. As a demonstration of the power of such materials, the resulting Cyt c embedded in ZIF-8 showed a 10-fold increase in peroxidase activity compared to free Cyt c in solution and thus gave convenient, fast, and highly sensitive detection of trace amounts of explosive organic peroxides in solution.
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5Topics & keywords
Topics
Keywords
- Coprecipitation
- Metal-organic framework
- Molecule
- Organic molecules
- Chemistry
- Nanotechnology
- Peroxidase
- Metal
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