Multilocus Sequence Typing of Klebsiella pneumoniae Nosocomial Isolates
Inserm · Institut Pasteur · +1 more institution
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Abstract
A multilocus sequence typing (MLST) scheme was developed for Klebsiella pneumoniae. Sequences of seven housekeeping genes were obtained for 67 K. pneumoniae strains, including 19 ceftazidime- and ciprofloxacin-resistant isolates. Forty distinct allelic profiles were identified. MLST data were validated against ribotyping and showed high (96%) discriminatory power. The MLST approach provides unambiguous data useful for the epidemiology of K. pneumoniae isolates.
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5Topics & keywords
Topics
Keywords
- Multilocus sequence typing
- Klebsiella pneumoniae
- Housekeeping gene
- Biology
- Microbiology
- Typing
- Ribotyping
- Molecular epidemiology
UN Sustainable Development Goals
- Reduced inequalities
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