Biocompatibility of Graphene Oxide
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Abstract
Herein, we report the effects of graphene oxides on human fibroblast cells and mice with the aim of investigating graphene oxides' biocompatibility. The graphene oxides were prepared by the modified Hummers method and characterized by high-resolution transmission electron microscope and atomic force microscopy. The human fibroblast cells were cultured with different doses of graphene oxides for day 1 to day 5. Thirty mice divided into three test groups (low, middle, high dose) and one control group were injected with 0.1, 0.25, and 0.4 mg graphene oxides, respectively, and were raised for 1 day, 7 days, and 30 days, respectively. Results showed that the water-soluble graphene oxides were successfully prepared;…
Citation impact
1,050
total citations
- FWCI
- 33.04
- Percentile
- 100%
- References
- 36
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Authors
7Topics & keywords
Topics
Keywords
- Graphene
- Biocompatibility
- Toxicity
- Cytotoxicity
- Apoptosis
- Nanotoxicology
- Fibroblast
- Spleen
UN Sustainable Development Goals
- Clean water and sanitation
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