articleCurrent BiologySep 1, 2004BRONZE OA

Inappropriate Activation of the TSC/Rheb/mTOR/S6K Cassette Induces IRS1/2 Depletion, Insulin Resistance, and Cell Survival Deficiencies

OJO. Jameel ShahZWZhiyong WangTHTony Hunter

Salk Institute for Biological Studies

PubMed
Indexed incrossrefpubmed

Abstract

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Topics & keywords

Topics
Keywords
  • RHEB
  • TSC2
  • TSC1
  • Biology
  • PI3K/AKT/mTOR pathway
  • P70-S6 Kinase 1
  • Cancer research
  • Protein kinase B
UN Sustainable Development Goals
  • Good health and well-being
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