Development and Validation of a Risk Score for Predicting Death in Chagas' Heart Disease

Rassi, Anis; Rassi, Anis; Little, William C.; Xavier, Sérgio Salles; Rassi, Sérgio Gabriel; Rassi, A.; Rassi, Gustavo Gabriel; Hasslocher‐Moreno, Alejandro Marcel; Sousa, Andréa Silvestre de; Scanavacca, Maurício

doi:10.1056/nejmoa053241

articleNew England Journal of MedicineAug 23, 2006BRONZE OA

Development and Validation of a Risk Score for Predicting Death in Chagas' Heart Disease

ARAnis Rassi ARAnis Rassi WCWilliam C. Little SSSérgio Salles Xavier SGSérgio Gabriel Rassi

Hospital Araújo Jorge · Fundação Oswaldo Cruz · +3 more institutions

PubMed

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Abstract

Background

Chagas' disease is an important health problem in Latin America, and cardiac involvement is associated with substantial morbidity and mortality. We developed a model to predict the risk of death in patients with Chagas' heart disease.

Methods

We retrospectively evaluated 424 outpatients from a regional Brazilian cohort. The association of potential risk factors with death was tested by Cox proportional-hazards analysis, and a risk score was created. The model was validated in 153 patients from a separate community hospital.

Citation impact

638

total citations

FWCI: 21.62
Percentile: 100%
References: 19

Citations per year

Authors

10

Topics & keywords

Topics

Keywords

Medicine
Cohort
Internal medicine
Framingham Risk Score
Ventricular tachycardia
Proportional hazards model
Cardiology
Disease

UN Sustainable Development Goals

Good health and well-being

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