Bio-Bar-Code-Based DNA Detection with PCR-like Sensitivity

Nam, Jwa‐Min; Stoeva, Savka I.; Mirkin, Chad A.

doi:10.1021/ja049384+

articleJournal of the American Chemical SocietyApr 27, 2004Closed access

Bio-Bar-Code-Based DNA Detection with PCR-like Sensitivity

JNJwa‐Min Nam SISavka I. Stoeva CAChad A. Mirkin

Northwestern University

PubMed

Indexed incrossrefpubmed

Abstract

Novel two-component oligonucleotide-modified nanoparticle probes have been designed and used in a bio-bar-code assay with a 500 zeptomolar target DNA sensitivity limit.

Citation impact

741

total citations

FWCI: 13.40
Percentile: 100%
References: 13

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Authors

3

Topics & keywords

Topics

Keywords

Chemistry
Oligonucleotide
Sensitivity (control systems)
Bar (unit)
DNA
Detection limit
Code (set theory)
Molecular biology

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