reviewJournal of Clinical InvestigationNov 15, 2002Closed access

Orchestrating the unfolded protein response in health and disease

RJRandal J. Kaufman

Howard Hughes Medical Institute

PubMed
Indexed incrossrefdoajpubmed

Abstract

Nonstandard abbreviations used: endoplasmic reticulum (ER); unfolded protein response (UPR); basic leucine zipper (bZIP); UPR element (UPRE); endoplasmic reticulum stress response element (ERSE); site-1 protease (S1P); site-2 protease (S2P); sterol-response element-binding protein (SREBP); eukaryotic translation initiation factor 2 (eIF2); endoplasmic reticulum-associated degradation (ERAD); α1-proteinase

Citation impact

1,168
total citations
FWCI
19.70
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100%
References
94
Citations per year

Authors

1

Topics & keywords

Topics
Keywords
  • Endoplasmic reticulum
  • Unfolded protein response
  • Endoplasmic-reticulum-associated protein degradation
  • Leucine zipper
  • Cell biology
  • XBP1
  • Sterol regulatory element-binding protein
  • Protease
UN Sustainable Development Goals
  • Good health and well-being
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