articleNature MethodsSep 15, 2013HYBRID OA

IntOGen-mutations identifies cancer drivers across tumor types

Pompeu Fabra University · Institució Catalana de Recerca i Estudis Avançats

PubMed
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Abstract

IntOGen-mutations is a discovery tool for cancer researchers to find driver mutations in genes and pathways. The IntOGen-mutations platform ( http://www.intogen.org/mutations/ ) summarizes somatic mutations, genes and pathways involved in tumorigenesis. It identifies and visualizes cancer drivers, analyzing 4,623 exomes from 13 cancer sites. It provides support to cancer researchers, aids the identification of drivers across tumor cohorts and helps rank mutations for better clinical decision-making.

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Authors

8

Topics & keywords

Keywords
  • Carcinogenesis
  • Biology
  • Cancer
  • Exome sequencing
  • Exome
  • Identification (biology)
  • Mutation
  • Genetics
UN Sustainable Development Goals
  • Peace, Justice and strong institutions
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