Hierarchical modularity in human brain functional networks

The idea that complex systems have a hierarchical modular organization originated in the early 1960s and has recently attracted fresh support from quantitative studies of large scale, real-life networks. Here we investigate the hierarchical modular (or "modules-within-modules") decomposition of human brain functional networks, measured using functional magnetic resonance imaging in 18 healthy volunteers under no-task or resting conditions. We used a customized template to extract networks with more than 1800 regional nodes, and we applied a fast algorithm to identify nested modular structure at several hierarchical levels. We used mutual information, 0

• G
  GlaxoSmithKline
• NI
  National Institutes of Health
• MR
  Medical Research Council
• EA
  Engineering and Physical Sciences Research Council
• NH
  National Health and Medical Research Council

  Award: 454797
• NI
  National Institute of Mental Health
• NI
  National Institute of Biomedical Imaging and Bioengineering