articleLaser & Photonics ReviewSep 26, 2011GREEN OA

Integrated optical devices for lab‐on‐a‐chip biosensing applications

Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine

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Abstract

Abstract The application of portable, easy‐to‐use and highly sensitive lab‐on‐a‐chip biosensing devices for real‐time diagnosis could offer significant advantages over current analytical methods. Integrated optics‐based biosensors have become the most suitable technology for lab‐on‐chip integration due to their ability for miniaturization, their extreme sensitivity, robustness, reliability, and their potential for multiplexing and mass production at low cost. This review provides an extended overview of the state‐of‐the‐art in integrated photonic biosensors technology including interferometers, grating couplers, microring resonators, photonic crystals and other novel nanophotonic transducers. Particular…

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