Binding and Condensation of Plasmid DNA onto Functionalized Carbon Nanotubes: Toward the Construction of Nanotube-Based Gene Delivery Vectors
Centre National de la Recherche Scientifique · Immunologie, Immunopathologie et Chimie Thérapeutique · +1 more institution
Abstract
Carbon nanotubes (CNTs) constitute a class of nanomaterials that possess characteristics suitable for a variety of possible applications. Their compatibility with aqueous environments has been made possible by the chemical functionalization of their surface, allowing for exploration of their interactions with biological components including mammalian cells. Functionalized CNTs (f-CNTs) are being intensively explored in advanced biotechnological applications ranging from molecular biosensors to cellular growth substrates. We have been exploring the potential of f-CNTs as delivery vehicles of biologically active molecules in view of possible biomedical applications, including vaccination and gene delivery.…
Citation impact
- FWCI
- 26.38
- Percentile
- 100%
- References
- 38
Authors
10- RSRavi SinghCorresponding
Centre National de la Recherche Scientifique, Immunologie, Immunopathologie et Chimie Thérapeutique, Institut de Biologie Moléculaire et Cellulaire
- DPDavide Pantarotto
Centre National de la Recherche Scientifique, Immunologie, Immunopathologie et Chimie Thérapeutique, Institut de Biologie Moléculaire et Cellulaire
- DMDavid McCarthy
Centre National de la Recherche Scientifique, Immunologie, Immunopathologie et Chimie Thérapeutique, Institut de Biologie Moléculaire et Cellulaire
- OCOlivier Chaloin
Centre National de la Recherche Scientifique, Immunologie, Immunopathologie et Chimie Thérapeutique, Institut de Biologie Moléculaire et Cellulaire
- JHJohan Hoebeke
Centre National de la Recherche Scientifique, Immunologie, Immunopathologie et Chimie Thérapeutique, Institut de Biologie Moléculaire et Cellulaire
Topics & keywords
- Carbon nanotube
- Nanotechnology
- Surface modification
- Chemistry
- Gene delivery
- Nanotube
- DNA
- Biosensor