Sperm DNA integrity assessment in prediction of assisted reproduction technology outcome
Scania (Sweden) · Lund University · +3 more institutions
Indexed incrossrefpubmed
Abstract
Background
The sperm chromatin structure assay (SCSA) has been suggested as a predictor of fertility in vivo as well as in vitro. The available data however, have been based on limited numbers of treatments. We aimed to define the clinical role of SCSA in assisted reproduction.
Methods
A total of 998 cycles [387 intrauterine insemination (IUI), 388 IVF and 223 ICSI] from 637 couples were included. SCSA results were expressed as DNA fragmentation index (DFI) and high DNA stainable (HDS) cell fractions. Outcome parameters were biochemical pregnancy (BP), clinical pregnancy (CP) and delivery (D).
Citation impact
697
total citations
- FWCI
- 27.25
- Percentile
- 100%
- References
- 44
Citations per year
Authors
7Topics & keywords
Topics
Keywords
- Gynecology
- Insemination
- Andrology
- Fertility
- Biology
- Intrauterine insemination
- Assisted reproductive technology
- Sperm
UN Sustainable Development Goals
- Good health and well-being
No related works found for this paper.