articleArteriosclerosis Thrombosis and Vascular BiologyJan 1, 2003Closed access

Association of Hypoadiponectinemia With Coronary Artery Disease in Men

Toyonaka Municipal Hospital · Norwegian Womens Public Health Association · +3 more institutions

PubMed
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Abstract

BACKGROUND: Adiponectin is an adipocyte-derived plasma protein that accumulates in the injured artery and has potential antiatherogenic properties. This study was designed to determine whether a decreased plasma adiponectin level (hypoadiponectinemia) can be independently associated with the prevalence of coronary artery disease (CAD). METHODS AND RESULTS: The consecutive 225 male patients were enrolled from inpatients who underwent coronary angiography. Voluntary blood donors (n=225) matched for age served as controls. Plasma adiponectin levels in the CAD patients were significantly lower than those in the control subjects. Multiple logistic regression analysis including plasma adiponectin level, diabetes…

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