articleNeurologyAug 7, 2014HYBRID OA

Vitamin D and the risk of dementia and Alzheimer disease

University of Pittsburgh · Florida International University · +5 more institutions

PubMed
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Abstract

Objective

To determine whether low vitamin D concentrations are associated with an increased risk of incident all-cause dementia and Alzheimer disease.

Methods

One thousand six hundred fifty-eight elderly ambulatory adults free from dementia, cardiovascular disease, and stroke who participated in the US population-based Cardiovascular Health Study between 1992-1993 and 1999 were included. Serum 25-hydroxyvitamin D (25(OH)D) concentrations were determined by liquid chromatography-tandem mass spectrometry from blood samples collected in 1992-1993. Incident all-cause dementia and Alzheimer disease status were assessed during follow-up using National Institute of Neurological and Communicative Disorders and Stroke/Alzheimer's Disease and Related Disorders Association criteria.

Citation impact

560
total citations
FWCI
33.13
Percentile
100%
References
39
Citations per year

Authors

14

Topics & keywords

Keywords
  • Dementia
  • Hazard ratio
  • Medicine
  • Internal medicine
  • Vitamin D and neurology
  • Proportional hazards model
  • Stroke (engine)
  • Population
UN Sustainable Development Goals
  • Good health and well-being
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Funding