Nasal CPAP or Intubation at Birth for Very Preterm Infants
Royal Women's Hospital · Royal Children's Hospital · +5 more institutions
Abstract
Bronchopulmonary dysplasia is associated with ventilation and oxygen treatment. This randomized trial investigated whether nasal continuous positive airway pressure (CPAP), rather than intubation and ventilation, shortly after birth would reduce the rate of death or bronchopulmonary dysplasia in very preterm infants.
We randomly assigned 610 infants who were born at 25-to-28-weeks' gestation to CPAP or intubation and ventilation at 5 minutes after birth. We assessed outcomes at 28 days of age, at 36 weeks' gestational age, and before discharge.
Citation impact
- FWCI
- 68.91
- Percentile
- 100%
- References
- 43
Authors
6- CJColin J. MorleyCorresponding
Royal Women's Hospital, Royal Children's Hospital, University of Melbourne
- PGPeter G. Davis
University of Melbourne, Royal Women's Hospital
- LWLex W. Doyle
University of Melbourne, Royal Women's Hospital
- LPLuc P. Brion
Albert Einstein College of Medicine, Children's Hospital at Montefiore
- JHJean-Michel Hascoët
Centre Hospitalier Régional et Universitaire de Nancy
Topics & keywords
- Medicine
- Bronchopulmonary dysplasia
- Continuous positive airway pressure
- Intubation
- Odds ratio
- Anesthesia
- Gestational age
- Gestation
- Good health and well-being