reviewPLoS Computational BiologyOct 30, 2008GOLD OA

Support Vector Machines and Kernels for Computational Biology

Colorado State University · Max Planck Society · +3 more institutions

PubMed
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Abstract

The increasing wealth of biological data coming from a large variety of platforms and the continued development of new high-throughput methods for probing biological systems require increasingly more sophisticated computational approaches. Putting all these data in simple-to-use databases is a first step; but realizing the full potential of the data requires algorithms that automatically extract regularities from the data, which can then lead to biological insight. Many of the problems in computational biology are in the form of prediction: starting from prediction of a gene's structure, prediction of its function, interactions, and role in disease. Support vector machines (SVMs) and related kernel methods are…

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