Epidemiology and Outcome of Mould Infections in Hematopoietic Stem Cell Transplant Recipients
Fred Hutch Cancer Center · University of Washington · +2 more institutions
Abstract
Reports have focused on the emergence of moulds as pathogens in recipients of hematopoietic stem cell transplants. To review the incidence of and risks for mould infections, we examined the records of 5589 patients who underwent hematopoietic stem cell transplantation at the Fred Hutchinson Cancer Research Center (Seattle) from 1985 through 1999. After 1992, the incidence of invasive aspergillosis increased in allograft recipients and remained high through the 1990s. Infections with non-fumigatus Aspergillus species, Fusarium species, and Zygomycetes increased during the late 1990s, especially in patients who received multiple transplants. Although infection caused by Scedosporium species was common in…
Citation impact
- FWCI
- 34.32
- Percentile
- 100%
- References
- 32
Authors
5- KAKieren A. MarrCorresponding
Fred Hutch Cancer Center, University of Washington, Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa, Cancer Research Center
- RARachel A. Carter
Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa, Cancer Research Center, Fred Hutch Cancer Center
- FCFulvio Crippa
Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa, Cancer Research Center, Fred Hutch Cancer Center
- AWAnna Wald
Cancer Research Center, Fred Hutch Cancer Center, Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa, University of Washington
- LCLawrence Corey
Cancer Research Center, University of Washington, Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa, Fred Hutch Cancer Center
Topics & keywords
- Hematopoietic stem cell transplantation
- Neutropenia
- Epidemiology
- Aspergillosis
- Medicine
- Incidence (geometry)
- Transplantation
- Mucormycosis