articleNature MedicineJan 17, 2010GREEN OA

Neutrophil elastase–mediated degradation of IRS-1 accelerates lung tumor growth

AMA. McGarry HoughtonDMDanuta M. RzymkiewiczHJHongbin JiADAlyssa D. GregoryEEEduardo Egea

University of Pittsburgh · Brigham and Women's Hospital · +6 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

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Citation impact

733
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FWCI
12.73
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100%
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36
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Authors

16

Topics & keywords

Topics
Keywords
  • Neutrophil elastase
  • Cancer research
  • Biology
  • Elastase
  • Tumor progression
  • PI3K/AKT/mTOR pathway
  • Neutrophil extracellular traps
  • Lung cancer
UN Sustainable Development Goals
  • Good health and well-being
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