Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain

Insufficient sleep is associated with obesity, yet little is known about how repeated nights of insufficient sleep influence energy expenditure and balance. We studied 16 adults in a 14- to 15-d-long inpatient study and quantified effects of 5 d of insufficient sleep, equivalent to a work week, on energy expenditure and energy intake compared with adequate sleep. We found that insufficient sleep increased total daily energy expenditure by ∼5%; however, energy intake--especially at night after dinner--was in excess of energy needed to maintain energy balance. Insufficient sleep led to 0.82 ± 0.47 kg (±SD) weight gain despite changes in hunger and satiety hormones ghrelin and leptin, and peptide YY, which…

• NI
  National Institutes of Health

  Awards: R01 HL109706, TR000154, HL109706, UL1 TR000154
• DF
  Directorate for Biological Sciences
• NC
  National Center for Advancing Translational Sciences

  Award: UL1 TR000154
• CC
  Colorado Clinical and Translational Sciences Institute

  Awards: UL1 TR000154, TR000154