articleJournal of Neurology Neurosurgery & PsychiatryJul 16, 2004BRONZE OA

Recommended diagnostic criteria for paraneoplastic neurological syndromes

FGFrancesc Graus

Universitat de Barcelona

PubMed
Indexed incrossrefpubmed

Abstract

The entopeduncular nucleus (EPN) and substantia nigra pars reticulata (SNr) constitute the output nuclei of the basal ganglia, but studies on the EPN are limited compared with those on the SNr. Both nuclei receive projections from the striatum with axons containing substance P (SP) and cannabinoid type-1 receptor (CB1R), and immunoreactivities for these substances show complementary patterns in the striatum and SNr. In this study we revealed a similar complementarity in the mouse EPN, combined it with region-specific neuronal distributions, and defined subregions of the EPN. First, the EPN was divided into two areas, one showing low SP and high CB1R (lSP/hCB1R) immunoreactivities and the other showing opposite…

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Topics & keywords

Topics
Keywords
  • Basal ganglia
  • Striatum
  • Neuroscience
  • Nucleus accumbens
  • Habenula
  • Substantia nigra
  • Pars reticulata
  • Biology
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