Direct-write bioprinting of cell-laden methacrylated gelatin hydrogels
Brigham and Women's Hospital · Harvard–MIT Division of Health Sciences and Technology · +6 more institutions
Abstract
Fabrication of three dimensional (3D) organoids with controlled microarchitectures has been shown to enhance tissue functionality. Bioprinting can be used to precisely position cells and cell-laden materials to generate controlled tissue architecture. Therefore, it represents an exciting alternative for organ fabrication. Despite the rapid progress in the field, the development of printing processes that can be used to fabricate macroscale tissue constructs from ECM-derived hydrogels has remained a challenge. Here we report a strategy for bioprinting of photolabile cell-laden methacrylated gelatin (GelMA) hydrogels. We bioprinted cell-laden GelMA at concentrations ranging from 7 to 15% with varying cell…
Citation impact
- FWCI
- 30.58
- Percentile
- 100%
- References
- 37
Authors
11- LELuiz E. Bertassoni
Brigham and Women's Hospital, Harvard–MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, University of Sydney, Harvard University
- JCJuliana Cordeiro Cardoso
Massachusetts Institute of Technology, Harvard–MIT Division of Health Sciences and Technology, Brigham and Women's Hospital, Harvard University, Universidade Tiradentes
- VMVijayan Manoharan
SASTRA University, Massachusetts Institute of Technology, Harvard University, Harvard–MIT Division of Health Sciences and Technology, Brigham and Women's Hospital
- ALAna Luiza Cristino
Harvard University, Brigham and Women's Hospital, Massachusetts Institute of Technology, Harvard–MIT Division of Health Sciences and Technology
- NSNupura S. Bhise
Harvard University, Massachusetts Institute of Technology, Harvard–MIT Division of Health Sciences and Technology, Brigham and Women's Hospital
Topics & keywords
- Self-healing hydrogels
- Gelatin
- Tissue engineering
- 3D bioprinting
- Nanotechnology
- Materials science
- Fabrication
- Biofabrication