Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study
The Royal Free Hospital · University College London · +14 more institutions
Abstract
Earlier detection of pulmonary arterial hypertension (PAH), a leading cause of death in systemic sclerosis (SSc), facilitates earlier treatment. The objective of this study was to develop the first evidence-based detection algorithm for PAH in SSc.
In this cross-sectional, international study conducted in 62 experienced centres from North America, Europe and Asia, adults with SSc at increased risk of PAH (SSc for >3 years and predicted pulmonary diffusing capacity for carbon monoxide
Citation impact
- FWCI
- 42.10
- Percentile
- 100%
- References
- 41
Authors
15- GCGerry CoghlanCorresponding
The Royal Free Hospital, University College London
- CPChristopher P. Denton
The Royal Free Hospital, University College London
- EGEkkehard Grünig
Heidelberg University, University Hospital Heidelberg
- DBDiana Bonderman
Medical University of Vienna
- ODOliver Distler
University Hospital of Zurich
Topics & keywords
- Medicine
- Pulmonary hypertension
- Referral
- Internal medicine
- Cardiology
- Nomogram
- Medical diagnosis
- Radiology
- Reduced inequalities
Funding
- AAmgen
- BSBristol-Myers Squibb
- ELEli Lilly and Company
- PPfizer
- GGlaxoSmithKline
- SSanofi
- GSGilead Sciences
- TPTeva Pharmaceutical Industries
- CCelgene
- FFibroGen
- UTUnited Therapeutics Corporation
- UOUniversity of Michigan
- AFAlbert-Ludwigs-Universität Freiburg
- MMedac
- GGenentech
- DODivision of Materials Research
- APActelion Pharmaceuticals