articleCancer CellDec 1, 2010BRONZE OA

Acquired Resistance to BRAF Inhibitors Mediated by a RAF Kinase Switch in Melanoma Can Be Overcome by Cotargeting MEK and IGF-1R/PI3K

JVJessie VillanuevaAVAdina VulturJTJohn Tayu LeeRSRajasekharan SomasundaramMFMizuho Fukunaga‐Kalabis

The Wistar Institute · University of Pennsylvania · +3 more institutions

PubMed
Indexed incrossrefpubmed

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1,231
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21

Topics & keywords

Topics
Keywords
  • PI3K/AKT/mTOR pathway
  • Kinase
  • Melanoma
  • Cancer research
  • MEK inhibitor
  • MAPK/ERK pathway
  • Biology
  • Chemistry
UN Sustainable Development Goals
  • Good health and well-being
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