Biological insights from 108 schizophrenia-associated genetic loci

Goldstein, Jacqueline I.; Lee, Phil; Ripke, Stephan; Huang, Hailiang; Farh, Kai-How; Daly, Mark J.; Neale, Benjamin M.; Bulik‐Sullivan, Brendan; Fromer, Menachem; Chambert, Kimberly D.; Genovese, Giulio; Smoller, Jordan W.; Lee, Phil; Scolnick, Edward M.; Ripke, Stephan; Bevilacqua, Elizabeth; Moran, Jennifer L.; Palotie, Aarno; Petryshen, Tracey L.; Belliveau, Richard A.; McCarroll, Steven A.; Bergen, Sarah E.; Daly, Mark J.; Neale, Benjamin M.; Bulik-Sullivan, Brendan; O’Dushlaine, Colm; Fromer, Menachem; Stahl, Eli A.; Goldstein, Jacqueline I.; Esko, Tõnu; Neale, Benjamin M.; Pers, Tune H.; Huang, Hailiang; Hirschhorn, Joel N.; Price, Alkes L.; Daly, Mark J.; Lee, Phil; Fromer, Menachem; Neale, Benjamin M.; Smoller, Jordan W.; Palotie, Aarno; Cormican, Paul; Corvin, Aiden; Gill, Michael; Donohoe, Gary; Morris, Derek W.; Richards, Alexander; Ruderfer, Douglas M.; Owen, Michael J.; Carrera, Noa; Hamshere, Marian L.; Craddock, Nick; Kavanagh, David; O’Donovan, Michael C.; Holmans, Peter; Kirov, George; Legge, Sophie E.; Escott‐Price, Valentina; Williams, Nigel; Pocklington, Andrew; Georgieva, Lyudmila; Walters, James; Craddock, Nick; O’Donovan, Michael C.; Owen, Michael J.; Holmans, Peter; Collier, David; Mokrab, Younes; Collier, David; Pers, Tune H.; Esko, Tõnu; Pers, Tune H.; Hirschhorn, Joel N.; Söderman, Erik; Agartz, Ingrid; Jönsson, Erik G.; Agartz, Ingrid; Djurovic, Srdjan; Mattingsdal, Morten; Agartz, Ingrid; Andreassen, Ole A.; Jönsson, Erik G.; Melle, Ingrid; Agerbo, Esben; Mortensen, Preben Bo; Agerbo, Esben; Mortensen, Preben Bo; Mortensen, Preben Bo; Børglum, Anders D.; Rasmussen, Henrik B.; Demontis, Ditte; Agerbo, Esben; Olsen, Line; Mattheisen, Manuel; Mors, Ole; Werge, Thomas; Hansen, Thomas Folkmann; Albus, Margot; Alexander, Madeline; Laurent, Claudine; Levinson, Douglas F.; Amin, Farooq; Amin, Farooq; Bacanu, Silviu‐Alin; Webb, Bradley T.; Bigdeli, Tim B.; Wormley, Brandon; Hammer, Christian; Begemann, Martin; Papiol, Sergi; Ehrenreich, Hannelore; Bene, Judit; Melegh, Béla; Bene, Judit; Melegh, Béla; Hultman, Christina M.; Magnusson, Patrik K. E.; Sullivan, Patrick F.; Kähler, Anna K.; Bergen, Sarah E.; Black, Donald W.; Bruggeman, Richard; Buccola, Nancy G.; Roffman, Joshua L.; Buckner, Randy L.; Buckner, Randy L.; Roffman, Joshua L.; Buckner, Randy L.; Byerley, William; Ophoff, Roel A.; Kahn, René S.; Cahn, Wiepke; Strengman, Eric; Buxbaum, Joseph D.; Cai, Guiqing; Silverman, Jeremy M.; Haroutunian, Vahram; Buxbaum, Joseph D.; Parkhomenko, Elena; Friedman, Joseph I.; Drapeau, Elodie; Cai, Guiqing; Davis, Kenneth L.; Reichenberg, Abraham; Campion, Dominique; Ophoff, Roel A.; Cantor, Rita M.; Henskens, Frans; Carr, Vaughan J.; Pantelis, Christos; Loughland, Carmel M.; Michie, Patricia T.; Jablensky, Assen V.; Scott, Rodney J.; Catts, Stanley V.; Schall, Ulrich; Carr, Vaughan J.; Catts, Stanley V.; Chan, Raymond; So, Hon‐Cheong; Chen, Ronald Y.L.; Sham, Pak C.; Wong, Emily; Chen, Eric; Li, Miaoxin; Li, Miaoxin; Chen, Eric; Sham, Pak C.; Cheng, Wei; Cheung, Eric; Lee, Jimmy; Chong, Siow Ann; Sim, Kang; Subramaniam, Mythily; Cloninger, C. Robert; Švrakić, Dragan M.; Cohen, David; Cohen, Nadine; Kim, Yunjung; Williams, Stephanie; Farrell, Martilias S.; Crowley, James J.; Giusti‐Rodríguez, Paola; Sullivan, Patrick F.; Szatkiewicz, Jin; Curtis, David; Curtis, David; Pimm, Jonathan; McQuillin, Andrew; Gurling, Hugh; Davidson, Michael; Weiser, Mark; Cichon, Sven; Degenhardt, Franziska; Hofman, Andrea; Hoffmann, Per; Nöthen, Markus M.; Herms, Stefan; Cichon, Sven; Degenhardt, Franziska; Hofman, Andrea; Hoffmann, Per; Nöthen, Markus M.; Herms, Stefan; Del‐Favero, Jurgen; Børglum, Anders D.; Mattheisen, Manuel; Mors, Ole; Demontis, Ditte; Børglum, Anders D.; Mattheisen, Manuel; Demontis, Ditte; Papadimitriou, George N.; Dikeos, Dimitris; Dinan, Timothy G.; Djurovic, Srdjan; Donohoe, Gary; Morris, Derek W.; Duan, Jubao; Sanders, Alan R.; Gejman, Pablo V.; Duan, Jubao; Sanders, Alan R.; Gejman, Pablo V.; Dudbridge, Frank; Durmishi, Naser; Eichhammer, Peter; Eriksson, Johan G.; Eriksson, Johan G.; Salomaa, Veikko; Eriksson, Johan G.; Essioux, Laurent; Fanous, Ayman H.; Fanous, Ayman H.; Fanous, Ayman H.; Fanous, Ayman H.; Schulze, Thomas G.; Witt, Stephanie H.; Strohmaier, Jana; Meier, Sandra; Frank, Josef; Rietschel, Marcella; Franke, Lude; Karjalainen, Juha; Olincy, Ann; Freedman, Robert; Freimer, Nelson B.; Ophoff, Roel A.; Friedl, Marion; Giegling, Ina; Konte, Bettina; Hartmann, Annette M.; Rujescu, Dan; Ruderfer, Douglas M.; Stahl, Eli A.; Sklar, Pamela; Fromer, Menachem; Purcell, Shaun; Roussos, Panos; Rujescu, Dan; Giegling, Ina; Godard, Stephanie; Голимбет, В. Е.; Li, Qingqin S.; Gopal, Srihari; Wang, Dai; Wray, Naomi R.; Mowry, Bryan; Visscher, Peter M.; Gratten, Jacob; Lee, Sang; Haan, Lieuwe de; Meijer, Carin J.; Hansen, Mark; Hansen, Thomas Folkmann; Olsen, Line; Rasmussen, Henrik B.; Werge, Thomas; Haroutunian, Vahram; Sklar, Pamela; Buxbaum, Joseph D.; Haroutunian, Vahram; Henskens, Frans; Henskens, Frans; Herms, Stefan; Hoffmann, Per; Cichon, Sven; McCarroll, Steven A.; Esko, Tõnu; Hirschhorn, Joel N.; Hougaard, David M.; Hollegaard, Mads V.; Ikeda, Masashi; Iwata, Nakao; Joa, Inge; Marsal, Sara; Julià, Antonio; Kalaydjieva, Luba; Kalaydjieva, Luba; Jablensky, Assen V.; Тончева, Драга; Karachanak-Yankova, Sena; Keller, Matthew C.; Zai, Clement C.; Knight, Jo; Kennedy, James L.; Zai, Clement C.; Knight, Jo; Kennedy, James L.; Kennedy, James L.; Knight, Jo; Slominsky, P. A.; Sa, Limborskaia; Khrunin, Andrey; Kloviņš, Jānis; Ņikitina-Zaķe, Liene; Pato, Carlos N.; Pato, Michele T.; Knowles, James A.; Kučinskas, Vaidutis; Kučinskienė, Zita Aušrelė; Kuzelova-Ptackova, Hana; Maçek, Milan; Laurent, Claudine; Lee, Jimmy; Lerer, Bernard; Sham, Pak C.; Li, Miaoxin; Wang, Qiang; Li, Tao; Liang, Kung‐Yee; Stroup, T. Scott; Lieberman, Jeffrey A.; Loughland, Carmel M.; Schall, Ulrich; Lubiński, Jan; Lönnqvist, Jouko; Suvisaari, Jaana; Lönnqvist, Jouko; Suvisaari, Jaana; Maher, Brion S.; Maier, Wolfgang; Mallet, Jacques; Mattheisen, Manuel; Mattingsdal, Morten; Seidman, Larry J.; Mesholam-Gately, Raquelle I.; McCarley, Robert W.; Petryshen, Tracey L.; McCarley, Robert W.; McDonald, Colm; McIntosh, Andrew M.; Blackwood, Douglas H. R.; McIntosh, Andrew M.; Andreassen, Ole A.; Melle, Ingrid; Mesholam-Gately, Raquelle I.; Seidman, Larry J.; Nelis, Mari; Metspalu, Andres; Milani, Lili; Esko, Tõnu; Michie, Patricia T.; Milanova, Vihra; Mors, Ole; Børglum, Anders D.; Murphy, Kieran C.; Murray, Robin; Powell, John; Myin‐Germeys, Inez; Os, Jim van; Müller-Myhsok, Bertram; Müller-Myhsok, Bertram; Müller-Myhsok, Bertram; Nenadić, Igor; Nertney, Deborah A.; Nestadt, Gerald; Pulver, Ann E.; Nicodemus, Kristin K.; Nisenbaum, Laura; Nordin, Annelie; Adolfsson, Rolf; O’Callaghan, Eadbhard; O’Neill, F. Anthony; Oh, Sang‐Yun; Os, Jim van; Pantelis, Christos; Paunio, Tiina; Paunio, Tiina; Pietiläinen, Olli; Pejović-Milovančević, Milica; Perkins, Diana O.; Sullivan, Patrick F.; Pietiläinen, Olli; Palotie, Aarno; Price, Alkes L.; Quested, Digby; Reimers, Mark A.; Wolen, Aaron R.; Sklar, Pamela; Roussos, Panos; Wendland, Jens R.; Schubert, Christian; Schulze, Thomas G.; Schwab, Sibylle G.; Scott, Rodney J.; Scott, Rodney J.; Shi, Jianxin; Sigurðsson, Engilbert; Silagadze, Teimuraz; Silverman, Jeremy M.; Spencer, ChrisC. A.; Stefánsson, Hreinn; Stefansson, Kari; Steinberg, Stacy; Stögmann, Elisabeth; Zimprich, Fritz; Weinberger, D.R.; Straub, Richard E.; Strengman, Eric; Thirumalai, Srinivas; Tosato, Sarah; Veijola, Juha; Veijola, Juha; Walsh, Dermot; Wildenauer, Dieter B.; Jablensky, Assen V.; Xi, Hualin Simon; Liu, Jianjun; Buxbaum, Joseph D.; Cichon, Sven; Darvasi, Ariel; Domenici, Enrico; Jablensky, Assen; Riley, Brien P.; Kendler, Kenneth S.; Lencz, Todd; Malhotra, Anil K.; Lencz, Todd; Malhotra, Anil K.; Lencz, Todd; Malhotra, Anil K.; Liu, Jianjun; Mowry, Bryan; Petryshen, Tracey L.; Posthuma, Daniëlle; Posthuma, Daniëlle; Posthuma, Daniëlle; Clair, David St; Weinberger, D.R.; Werge, Thomas

doi:10.1038/nature13595

articleNatureJul 1, 2014BRONZE OA

Biological insights from 108 schizophrenia-associated genetic loci

JIJacqueline I. GoldsteinPL Phil LeeSRStephan Ripke HHHailiang Huang KFKai-How Farh

Broad Institute · Harvard University Press · +205 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

8,065

total citations

FWCI: 543.49
Percentile: 100%
References: 57

Citations per year

Authors

451

JI
Jacqueline I. GoldsteinCorresponding
Broad Institute, Harvard University Press, Massachusetts General Hospital
PL
Phil Lee
Broad Institute, Harvard University Press, Massachusetts General Hospital, NeuroDevelopment Center
SR
Stephan Ripke
Broad Institute, Trinity College Dublin, Massachusetts General Hospital
HH
Hailiang Huang
Broad Institute, Massachusetts General Hospital, Cardiff University
KF
Kai-How Farh
Harvard University Press, Massachusetts General Hospital

Topics & keywords

Topics

Keywords

Schizophrenia (object-oriented programming)
Genome-wide association study
Genetic association
Biology
Genetics
Allele
Gene
Psychosis

UN Sustainable Development Goals

Good health and well-being

No related works found for this paper.