Specific light-up bioprobes based on AIEgen conjugates
National University of Singapore · Environmental Research Institute · +7 more institutions
Abstract
Driven by the high demand for sensitive and specific tools for optical sensing and imaging, bioprobes with various working mechanisms and advanced functionalities are flourishing at an incredible speed. Conventional fluorescent probes suffer from the notorious effect of aggregation-caused quenching that imposes limitation on their labelling efficiency or concentration to achieve desired sensitivity. The recently emerged fluorogens with an aggregation-induced emission (AIE) feature offer a timely remedy to tackle the challenge. Utilizing the unique properties of AIE fluorogens (AIEgens), specific light-up probes have been constructed through functionalization with recognition elements, showing advantages such…
Citation impact
- FWCI
- 42.40
- Percentile
- 100%
- References
- 50
Authors
3- JLJing Liang
National University of Singapore, Environmental Research Institute
- BZBen Zhong TangCorresponding
Hong Kong University of Science and Technology, Kowloon Hospital, Institute of Molecular Functional Materials, University of Hong Kong, South China University of Technology
- BLBin LiuCorresponding
Agency for Science, Technology and Research, National University of Singapore, Institute of Materials Research and Engineering
Topics & keywords
- Aggregation-induced emission
- Computer science
- Adaptability
- Nanotechnology
- Flourishing
- Materials science
- Biochemical engineering
- Fluorescence
- Good health and well-being
Funding
- NUNational University of SingaporeAward: R279-000-415-112
- HKHong Kong University of Science and Technology
- GPGuangdong Province Introduction of Innovative R&D TeamAward: 201101C0105067115
- IOInstitute of Materials Research and EngineeringAward: IMRE/14-8P1110
- NKNational Key Research and Development Program of ChinaAward: 2013CB834701