reviewVeterinary PathologySep 17, 2013Closed access

MicroRNAs

MBM. BhaskaranMMMahesh Mohan

Tulane University

PubMed
Indexed incrossrefpubmed

Abstract

The discovery of microRNAs (miRNAs) in 1993 followed by developments and discoveries in small RNA biology have redefined the biological landscape by significantly altering the longstanding dogmas that defined gene regulation. These small RNAs play a significant role in modulation of an array of physiological and pathological processes ranging from embryonic development to neoplastic progression. Unique miRNA signatures of various inherited, metabolic, infectious, and neoplastic diseases have added a new dimension to the studies that look at their pathogenesis and highlight their potential to be reliable biomarkers. Also, altering miRNA functionality and the development of novel in vivo delivery systems to…

Citation impact

610
total citations
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2.31
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100%
References
207
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Authors

2

Topics & keywords

Topics
Keywords
  • microRNA
  • Biology
  • Computational biology
  • Small RNA
  • Function (biology)
  • Bioinformatics
  • Gene
  • Genetics
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