Genomic evidence for the Pleistocene and recent population history of Native Americans

Raghavan, Maanasa; Steinrücken, Matthias; Harris, Kelley; Schiffels, Stephan; Rasmussen, Simon; DeGiorgio, Michael; Albrechtsen, Anders; Valdiosera, Cristina; Ávila‐Arcos, María C.; Malaspinas, Anna‐Sapfo; Eriksson, Anders; Moltke, Ida; Metspalu, Mait; Homburger, Julian R.; Wall, Jeff; Cornejo, Omar E.; Moreno-Mayar, J. Víctor; Korneliussen, Thorfinn Sand; Pierre, Tracey; Rasmussen, Morten; Campos, Paula F.; Damgaard, Peter de Barros; Allentoft, Morten E.; Lindo, John; Metspalu, Ene; Varela, Ricardo; Lory, Josefina Mansilla; Henrickson, Celeste; Seguin‐Orlando, Andaine; Malmström, Helena; Stafford, Thomas; Shringarpure, Suyash; Moreno‐Estrada, Andrés; Karmin, Monika; Tambets, Kristiina; Bergström, Anders; Xue, Yali; Warmuth, Vera; Friend, A. D.; Singarayer, Joy; Valdes, Paul J.; Balloux, François; Leboreiro, Ilán; Vera, José Luis; Rangel‐Villalobos, Héctor; Pettener, Davide; Luiselli, Donata; Davis, Loren G.; Heyer, Évelyne; Zollikofer, Christoph P. E.; León, Marcia S. Ponce de; Smith, Colin; Grimes, Vaughan; Pike, Kelly-Anne; Deal, Michael; Fuller, Benjamin T.; Arriaza, Bernardo; Standen, Vivien G.; Luz, Maria Francisca; Ricaut, François‐Xavier; Guidon, Niède; Osipova, L. P.; Voevoda, Mikhail I.; Posukh, Olga L.; Balanovsky, Oleg; Lavryashina, Maria; Bogunov, Yuri; Хуснутдинова, Э. К.; Gubina, Marina; Balanovska, Elena; Федорова, С.А.; Litvinov, Sergey; Malyarchuk, B. А.; Деренко, М. В.; Mosher, M. J.; Archer, David; Cybulski, Jerome S.; Petzelt, Barbara; Mitchell, Joycelynn; Worl, Rosita; Norman, Paul J.; Parham, Peter; Kemp, Brian M.; Kivisild, Toomas; Tyler-Smith, Chris; Sandhu, Manjinder S.; Crawford, Michael; Villems, Richard; Smith, David Glenn; Waters, Michael R.; Goebel, Ted; Johnson, John R.; Malhi, Ripan S.; Jakobsson, Mattias; Meltzer, David J.; Manica, Andrea; Durbin, Richard; Bustamante, Carlos D.; Song, Yun S.; Nielsen, Rasmus; Willerslev, Eske

doi:10.1126/science.aab3884

articleScienceJul 22, 2015GREEN OA

Genomic evidence for the Pleistocene and recent population history of Native Americans

MRMaanasa Raghavan MSMatthias Steinrücken KHKelley Harris SSStephan Schiffels SRSimon Rasmussen

University of Copenhagen · Natural History Museum Aarhus · +64 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including…

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Topics & keywords

Topics

Keywords

Pleistocene
Evolutionary biology
Population
Geography
Biology
Genealogy
History
Archaeology

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