articleNano LettersMar 31, 2005Closed access

Electrostatic Control of Ions and Molecules in Nanofluidic Transistors

University of California, Berkeley · Lawrence Berkeley National Laboratory

PubMed
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Abstract

We report a nanofluidic transistor based on a metal-oxide-solution (MOSol) system that is similar to a metal-oxide-semiconductor field-effect transistor (MOSFET). Using a combination of fluorescence and electrical measurements, we demonstrate that gate voltage modulates the concentration of ions and molecules in the channel and controls the ionic conductance. Our results illustrate the efficacy of field-effect control in nanofluidics, which could have broad implications on integrated nanofluidic circuits for manipulation of ions and biomolecules in sub-femtoliter volumes.

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