Comorbid Depressive and Anxiety Disorders in 509 Individuals With an At-Risk Mental State: Impact on Psychopathology and Transition to Psychosis
King's College London · South London and Maudsley NHS Foundation Trust · +3 more institutions
Abstract
The current diagnostic system for subjects at enhanced clinical risk of psychosis allows concurrent comorbid diagnoses of anxiety and depressive disorders. Their impact on the presenting high-risk psychopathology, functioning, and transition outcomes has not been widely researched.
In a large sample of subjects with an At-Risk Mental State (ARMS, n = 509), we estimated the prevalence of DSM/SCID anxiety or depressive disorders and their impact on psychopathology, functioning, and psychosis transition. A meta-analytical review of the literature complemented the analysis.
Citation impact
- FWCI
- 18.61
- Percentile
- 100%
- References
- 49
Authors
5- PFPaolo Fusar‐PoliCorresponding
King's College London, South London and Maudsley NHS Foundation Trust, Kings Health Partners
- BNBarnaby Nelson
The University of Melbourne, Orygen Youth Health
- LVLucia Valmaggia
King's College London, South London and Maudsley NHS Foundation Trust, Kings Health Partners
- ARAlison R. Yung
The University of Melbourne, Orygen Youth Health
- PMPhilip McGuire
King's College London, South London and Maudsley NHS Foundation Trust, Kings Health Partners
Topics & keywords
- Anxiety
- Psychopathology
- At risk mental state
- Psychiatry
- Psychosis
- Psychology
- Comorbidity
- Clinical psychology