Beyond post-synthesis modification: evolution of metal–organic frameworks via building block replacement

Metal-organic frameworks (MOFs) are hybrid porous materials with many potential applications, which intimately depend on the presence of chemical functionality either at the organic linkers and/or at the metal nodes. Functionality that cannot be introduced into MOFs directly via de novo syntheses can be accessed through post-synthesis modification (PSM) on the reactive moieties of the linkers and/or nodes without disrupting the metal-linker bonds. Even more intriguing methods that go beyond PSM are herein termed building block replacement (BBR) which encompasses (i) solvent-assisted linker exchange (SALE), (ii) non-bridging ligand replacement, and (iii) transmetalation. These one-step or tandem BBR processes…

• NU
  Northwestern University
• FN
  Fundacja na rzecz Nauki Polskiej
• DT
  Defense Threat Reduction Agency
• AR
  Advanced Research Projects Agency - Energy
• OO
  Office of Science
• AR
  Advanced Research Projects Agency
• BE
  Basic Energy Sciences
• AR
  Army Research Office