Heritability of Adult Body Height: A Comparative Study of Twin Cohorts in Eight Countries
University of Helsinki · Institute for Molecular Medicine Finland · +7 more institutions
Abstract
A major component of variation in body height is due to genetic differences, but environmental factors have a substantial contributory effect. In this study we aimed to analyse whether the genetic architecture of body height varies between affluent western societies. We analysed twin data from eight countries comprising 30,111 complete twin pairs by using the univariate genetic model of the Mx statistical package. Body height and zygosity were self-reported in seven populations and measured directly in one population. We found that there was substantial variation in mean body height between countries; body height was least in Italy (177 cm in men and 163 cm in women) and greatest in the Netherlands (184 cm and…
Citation impact
- FWCI
- 5.81
- Percentile
- 100%
- References
- 73
Authors
20Topics & keywords
- Heritability
- Zygosity
- Demography
- Twin study
- Additive genetic effects
- Genetic architecture
- Population
- Variance components
Funding
- AAstraZeneca
- EHEkstraStiftelsen Helse og Rehabilitering (Stiftelsen Dam)
- YJYrjö Jahnssonin Säätiö
- WTWellcome Trust
- CDChronic Disease Research Foundation
- BHBritish Heart Foundation
- ECEuropean CommissionAward: 01254
- AOAcademy of FinlandAward: 44069
- NFNorges Forskningsråd
- NINational Institutes of Health
- MRMedical Research Council
- NHNational Health and Medical Research Council
- NINorwegian Institute of Public Health
- NINational Institute on Alcohol Abuse and AlcoholismAward: AA 00145