Sarcopenia in an Overweight or Obese Patient Is an Adverse Prognostic Factor in Pancreatic Cancer
University of Alberta · University of Edinburgh
Abstract
PURPOSE: The average weight-losing pancreatic cancer patient undergoing palliative therapy is frequently overweight rather than underweight, and this can confound conventional measures used for risk stratification. The aim of this study was to evaluate if weight and body composition, specifically sarcopenia, assessed from diagnostic computed tomography (CT) scans, is of prognostic value in patients with pancreatic cancer. The nature and extent of tissue loss over subsequent months was also evaluated. EXPERIMENTAL DESIGN: A total of 111 patients entering a palliative therapy program, who had CT images and had undergone nutritional screening, were studied. In patients for whom follow-up scans were available (n =…
Citation impact
- FWCI
- 10.17
- Percentile
- 100%
- References
- 47
Authors
5- BTBenjamin Tan
University of Alberta, University of Edinburgh
- LBLaura Birdsell
University of Alberta, University of Edinburgh
- LMLisa Martin
University of Alberta, University of Edinburgh
- VEVickie E. BaracosCorresponding
University of Alberta, University of Edinburgh
- KCKenneth C. H. FearonCorresponding
University of Alberta, University of Edinburgh
Topics & keywords
- Medicine
- Overweight
- Sarcopenia
- Hazard ratio
- Pancreatic cancer
- Internal medicine
- Body mass index
- Confidence interval
- Zero hunger