The influence of puberty on subcortical brain development
University College London · National Institute of Mental Health · +1 more institution
Abstract
Puberty is characterized by hormonal, physical and psychological transformation. The human brain undergoes significant changes between childhood and adulthood, but little is known about how puberty influences its structural development. Using a longitudinal sample of 711 magnetic resonance imaging scans from 275 individuals aged 7-20years, we examined how subcortical brain regions change in relation to puberty. Our regions of interest included the amygdala, hippocampus and corpus striatum including the nucleus accumbens (NA), caudate, putamen and globus pallidus (GP). Pubertal development was significantly related to structural volume in all six regions in both sexes. Pubertal development and age had both…
Citation impact
- FWCI
- 39.92
- Percentile
- 100%
- References
- 55
Authors
6- AGAnne‐Lise GoddingsCorresponding
University College London
- KLKathryn L. Mills
National Institute of Mental Health, National Institutes of Health, University College London
- LCLiv Clasen
National Institute of Mental Health, National Institutes of Health
- JNJay N. Giedd
National Institute of Mental Health, National Institutes of Health
- RVRussell Viner
University College London
Topics & keywords
- Brain development
- Neuroscience
- Psychology
- Good health and well-being