Strategies for Heterocyclic Construction via Novel Multicomponent Reactions Based on Isocyanides and Nucleophilic Carbenes
National Institute for Interdisciplinary Science and Technology · Council of Scientific and Industrial Research · +2 more institutions
Abstract
This Account focuses mainly on our recent endeavors in the area of multicomponent reactions (MCRs) involving zwitterionic species generated by the addition of isocyanides and nucleophilic carbenes such as dimethoxycarbene and N-heterocyclic carbenes to activated alkynes. The strategy employed encompasses the interception of 1:1 zwitterionic species, generated in situ with a wide range of electrophiles. The new MCRs developed offer an efficient and convenient entry into several heterocycles of biological and synthetic importance.
Citation impact
- FWCI
- 17.22
- Percentile
- 100%
- References
- 18
Authors
7- VNVijay NairCorresponding
National Institute for Interdisciplinary Science and Technology, Council of Scientific and Industrial Research, Institute of Minerals and Materials Technology, Advanced Materials and Processes Research Institute
- CRC. Rajesh
Institute of Minerals and Materials Technology, Council of Scientific and Industrial Research, Advanced Materials and Processes Research Institute, National Institute for Interdisciplinary Science and Technology
- AUA. U. Vinod
Institute of Minerals and Materials Technology, Council of Scientific and Industrial Research, Advanced Materials and Processes Research Institute, National Institute for Interdisciplinary Science and Technology
- SBS. Bindu
Institute of Minerals and Materials Technology, National Institute for Interdisciplinary Science and Technology, Advanced Materials and Processes Research Institute, Council of Scientific and Industrial Research
- ARA. R. Sreekanth
Advanced Materials and Processes Research Institute, Council of Scientific and Industrial Research, Institute of Minerals and Materials Technology, National Institute for Interdisciplinary Science and Technology
Topics & keywords
- Electrophile
- Nucleophile
- Chemistry
- Combinatorial chemistry
- Organic chemistry
- Catalysis
- Life in Land