Default network connectivity reflects the level of consciousness in non-communicative brain-damaged patients
University of Liège · Cyclotron (Netherlands) · +6 more institutions
Abstract
The 'default network' is defined as a set of areas, encompassing posterior-cingulate/precuneus, anterior cingulate/mesiofrontal cortex and temporo-parietal junctions, that show more activity at rest than during attention-demanding tasks. Recent studies have shown that it is possible to reliably identify this network in the absence of any task, by resting state functional magnetic resonance imaging connectivity analyses in healthy volunteers. However, the functional significance of these spontaneous brain activity fluctuations remains unclear. The aim of this study was to test if the integrity of this resting-state connectivity pattern in the default network would differ in different pathological alterations of…
Citation impact
- FWCI
- 18.43
- Percentile
- 100%
- References
- 58
Authors
15- AVAudrey VanhaudenhuyseCorresponding
University of Liège
- QNQuentin Noirhomme
Cyclotron (Netherlands), University of Liège
- LTLuaba Tshibanda
University of Liège
- MBMarie‐Aurélie Bruno
University of Liège, Cyclotron (Netherlands)
- PBPierre Boveroux
Cyclotron (Netherlands), University of Liège, Centre Hospitalier Universitaire de Liège
Topics & keywords
- Default mode network
- Precuneus
- Posterior cingulate
- Psychology
- Minimally conscious state
- Resting state fMRI
- Functional magnetic resonance imaging
- Locked-in syndrome