reviewScience Translational MedicineDec 19, 2012GREEN OA

Hidden Killers: Human Fungal Infections

GDGordon D. BrownDWDavid W. DenningNANeil A. R. GowSMStuart M. LevitzMGMihai G. Netea

University of Aberdeen · National Computing Centre (United Kingdom) · +3 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Although fungal infections contribute substantially to human morbidity and mortality, the impact of these diseases on human health is not widely appreciated. Moreover, despite the urgent need for efficient diagnostic tests and safe and effective new drugs and vaccines, research into the pathophysiology of human fungal infections lags behind that of diseases caused by other pathogens. In this Review, we highlight the importance of fungi as human pathogens and discuss the challenges we face in combating the devastating invasive infections caused by these microorganisms, in particular in immunocompromised individuals.

Citation impact

4,286
total citations
FWCI
55.04
Percentile
100%
References
79
Citations per year

Authors

6

Topics & keywords

Topics
Keywords
  • Human health
  • Intensive care medicine
  • Medicine
  • Human pathogen
  • Immunology
  • Biology
  • Environmental health
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