articleMedicineSep 1, 2003GREEN OA

Morbidity and Mortality in Systemic Lupus Erythematosus During a 10-Year Period

RCRicard CerveraMAMunther A. KhamashtaJFJosep FontGDGian Domenico SebastianiAGAntonio Gil

Cliniques Universitaires Saint-Luc · Ankara University · +4 more institutions

PubMed
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Abstract

In the present study, we assessed the frequency and characteristics of the main causes of morbidity and mortality in systemic lupus erythematosus (SLE) during a 10-year period and compared the frequency of early manifestations with those that appeared later in the evolution of the disease. In 1990, we started a multicenter study of 1,000 patients from 7 European countries. All had medical histories documented and underwent medical interview and routine general physical examination when entered in the study, and all were followed prospectively by the same physicians during the ensuing 10 years (1990-2000).A total of 481 (48.1%) patients presented 1 or more episodes of arthritis at any time during the 10 years,…

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Topics & keywords

Topics
Keywords
  • Medicine
  • Serositis
  • Cytopenia
  • Rash
  • Malar rash
  • Pericarditis
  • Lupus erythematosus
  • Internal medicine
UN Sustainable Development Goals
  • Good health and well-being
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